Recombinant Human ALDOA Protein, His-tagged

Cat.No. : ALDOA-384H
Product Overview : Recombinant Human ALDOA(Met1-Tyr364), transcript variant 1, fused with His tag at C-terminal was expressed in E. coli.
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Species : Human
Source : E.coli
Tag : His
Protein Length : 1-364 a.a.
Description : The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.
Form : 20mM Tris-HCl, 100mM NaCl, 20% Glycerol, pH 8.0. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass : 40.5 kDa
Endotoxin : < 0.1 EU per µg protein as determined by LAL test
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name ALDOA aldolase A, fructose-bisphosphate [ Homo sapiens ]
Official Symbol ALDOA
Synonyms ALDOA; aldolase A, fructose-bisphosphate; fructose-bisphosphate aldolase A; muscle-type aldolase; lung cancer antigen NY-LU-1; fructose-1,6-bisphosphate triosephosphate-lyase; ALDA; GSD12;
Gene ID 226
mRNA Refseq NM_000034
Protein Refseq NP_000025
MIM 103850
UniProt ID P04075

Not For Human Consumption!

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