Recombinant Human AKAP8, His-tagged

• Cat.No.: AKAP8-3032H
• Product Overview: A-kinase anchor protein 8 (AKAP8)

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 692
• Description: This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of AKAP8 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: AKAP8 A kinase (PRKA) anchor protein 8 [ Homo sapiens ]
• Official Symbol: AKAP8
• Synonyms: AKAP8; A kinase (PRKA) anchor protein 8; A-kinase anchor protein 8; A kinase anchor protein; 95kDa; AKAP95; DKFZp586B1222; A-kinase anchor protein, 95kDa; AKAP-8; AKAP 95; AKAP-95
• Gene ID: 10270
• mRNA Refseq: NM_005858
• Protein Refseq: NP_005849
• MIM: 604692
• UniProt ID: O43823
• Chromosome Location: 19p13.1-q12
• Pathway: G Protein Signaling Pathways, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem
• Function: DNA binding; double-stranded DNA binding; metal ion binding; protein kinase A regulatory subunit binding; zinc ion binding