Recombinant Human AIG2-Like Domain 1, His-tagged

• Cat.No.: A2LD1-964H
• Product Overview: Recombinant human A2LD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: A2LD1, also known as gamma-glutamylaminecyclotransferase, is an enzyme that converts gamma-glutamylamines to free amines and 5-oxoproline. It shows high activity toward gamma-glutamyl-epsilon-lysine, derived from the breakdown of fibrin and other proteins cross-linked by transglutaminases. This protein adopts the newly identified cyclotransferase fold, observed in gamma-glutamylcyclotransferase, an enzyme with activity toward gamma-glutamyl-alpha-amino acids.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl.
• Molecular Weight: 19.4 kDa (173aa) confirmed by MALDI-TOF.
• Purity: > 95% by SDS - PAGE.
• Concentration: 1.0 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MALVFVYGTL KRGQPNHRVL RDGAHGSAAF RAR GRTLEPY PLVIAGEHNI PWLLHLPGSG RLVEGEVYAVDERMLRFLDD FESC PALYQR TVLRVQLLED RAPGAEEPPA PTAVQCFVYS RATFPPEWAQ LPH HD SYDSE GPHGLRYNPR ENR.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: A2LD1 AIG2-like domain 1 [ Homo sapiens ]
• Synonyms: AIG2-like domain 1; GGACT; A2LD1;gamma-glutamylaminecyclotransferase; OTTHU-MP00000018653; gamma-glutamylamine cyclotransferase; AIG2-like domain-contain-ing protein 1;EC 2.3.2.4; Gamma-glutamyl-aminecyclotransferase
• Gene ID: 87769
• mRNA Refseq: NM_001195087
• Protein Refseq: NP_001182016
• MIM: 613378
• UniProt ID: Q9BVM4
• Chromosome Location: 13q32.3
• Function: acyltransferase activity; gamma-glutamylcyclotransferase activity; transferase activity