Recombinant Human AHR protein, His-tagged

Cat.No. : AHR-120H
Product Overview : Recombinant Human AHR(Val128~Asn399) fused with His tag at N-terminal was expressed in E. coli.
Availability April 02, 2025
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Species : Human
Source : E.coli
Tag : His
Protein Length : Val128~Asn399
Description : The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300
Molecular Mass : 32.2kDa
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 97%
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name AHR aryl hydrocarbon receptor [ Homo sapiens ]
Official Symbol AHR
Synonyms AHR; aryl hydrocarbon receptor; bHLHe76; AH-receptor; ah receptor; aromatic hydrocarbon receptor; class E basic helix-loop-helix protein 76;
Gene ID 196
mRNA Refseq NM_001621
Protein Refseq NP_001612
MIM 600253
UniProt ID P35869
Chromosome Location 7p15
Pathway Adipogenesis, organism-specific biosystem;
Function DNA binding; DNA binding; Hsp90 protein binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; protein binding; protein dimerization activity; protein heterodimerization activity; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; signal transducer activity; transcription factor binding; transcription regulatory region DNA binding;

Not For Human Consumption!

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