Recombinant Human AGR3 Protein, His-tagged

• Cat.No.: AGR3-533H
• Product Overview: Recombinant Human AGR3 fused with His tag at C-terminal was expressed in HEK293.

Specification

• Description: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers.
• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized from a 0.2 µM filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM EDTA, pH 8.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
• Molecular Mass: 18.1 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Resuspend the protein to the desired concentration in proper buffer.

Gene Information

• Gene Name: AGR3 anterior gradient 3 homolog (Xenopus laevis) [ Homo sapiens ]
• Official Symbol: AGR3
• Synonyms: AGR3; anterior gradient 3 homolog (Xenopus laevis); anterior gradient protein 3 homolog; BCMP11; breast cancer membrane protein 11; hAG 3; HAG3; PDIA18; protein disulfide isomerase family A; member 18; AG-3; anterior gradient homolog 3; protein disulfide isomerase family A, member 18; AG3; hAG-3
• Gene ID: 155465
• mRNA Refseq: NM_176813
• Protein Refseq: NP_789783
• MIM: 609482
• UniProt ID: Q8TD06