Recombinant Human AFP Protein

• Cat.No.: AFP-0004H
• Product Overview: Recombinant Human AFP Protein without tag was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Description: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
• Applications: ELISA, CLIA, CG
• Notes: For research use only, not for use in diagnostic procedure.
• Storage: Short term (up to 7 days) store at 2–8 centigrade. Long term, store at - 20 centigrade. Avoid multiple freeze/thaw cycles.
• Storage Buffer: Supplied as a 0.2 μm filtered solution of PBS, pH7.4

Gene Information

• Gene Name: AFP alpha-fetoprotein [ Homo sapiens (human) ]
• Official Symbol: AFP
• Synonyms: AFP; alpha-fetoprotein; HPAFP; FETA; alpha-fetoglobulin; alpha-1-fetoprotein
• Gene ID: 174
• mRNA Refseq: NM_001134
• Protein Refseq: NP_001125
• MIM: 104150
• UniProt ID: P02771