Recombinant Human ADP-Ribosylhydrolase Like 2, His-tagged

• Cat.No.: ADPRHL2-2524H
• Product Overview: Recombinant human ADPRHL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Description: ADPRHL2 is a member of the ADP-ribosylglycohydrolase family. Expressed ubiquitously, ADPRHL2 uses magnesium as a cofactor to catalyze the hydrolysis of poly (ADP-ribose) that is synthesized after DNA damage. Also, ADPRHL2 plays an important role in the maintenance of normal neuronal cell function.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 30% glycerol, 1mM DTT.
• Molecular Mass: 41.5 kDa (387aa), confirmed by MALDI-TOF
• Protein length: 1-363aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAAAAM AAAAGGGAGA ARSLSRFRGC LAGALLGDCV GSFYEAHDTV DLTSVLRHVQ SLEPDPGTPG SERTEALYYT DDTAMARALV QSLLAKEAFD EVDMAHRFAQ EYKKDPDRGY GAGVVTVFKK LLNPKCRDVF EPARAQFNGK GSYGNGGAMR VAGISLAYSS VQDVQKFARL SAQLTHASSL GYNGAILQAL AVHLALQGES SSEHFLKQLL GHMEDLEGDA QSVLDARELG MEERPYSSRL KKIGELLDQA SVTREEVVSE LGNGIAAFES VPTAIYCFLR CMEPDPEIPS AFNSLQRTLI YSISLGGDTD TIATMAGAIA GAYYGMDQVP ESWQQSCEGY EETDILAQSL HRVFQKS
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ADPRHL2 ADP-ribosylhydrolase like 2 [ Homo sapiens ]
• Official Symbol: ADPRHL2
• Synonyms: ADPRHL2; ADP-ribosylhydrolase like 2; poly(ADP-ribose) glycohydrolase ARH3; ARH3; FLJ20446; ADP-ribosylhydrolase 3; protein ADP-ribosylarginine hydrolase-like protein 2; [Protein ADP-ribosylarginine] hydrolase-like protein 2
• Gene ID: 54936
• mRNA Refseq: NM_017825
• Protein Refseq: NP_060295
• MIM: 610624
• UniProt ID: Q9NX46
• Chromosome Location: 1p34.3
• Function: hydrolase activity; metal ion binding; poly(ADP-ribose) glycohydrolase activity