Recombinant Human ADNP protein, His & GST-tagged

• Cat.No.: ADNP-1701H
• Product Overview: Recombinant Human ADNP aa. (Ala528~Thr782 (Accession # Q9H2P0)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 58.6kDa
• Protein length: Ala528~Thr782
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 8.5

Gene Information

• Gene Name: ADNP activity dependent neuroprotector homeobox [ Homo sapiens (human) ]
• Official Symbol: ADNP
• Synonyms: ADNP; activity dependent neuroprotector homeobox; ADNP1; HVDAS; MRD28; activity-dependent neuroprotector homeobox protein; ADNP homeobox 1; activity-dependent neuroprotective protein; activity-dependent neuroprotector
• Gene ID: 23394
• mRNA Refseq: NM_001282531.2
• Protein Refseq: NP_001269460.1
• UniProt ID: Q9H2P0