Recombinant Human ADIPOR2, His-tagged, GST-tagged

• Cat.No.: ADIPOR2-3200H
• Product Overview: Adiponectin Receptor 2 (ADIPOR2)

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: 386
• Description: The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin.
• Form: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Molecular Mass: 49.8kDa
• Endotoxin: <1.0eu per 1ug (determined by the lal</1.0eu
• Purity: >95%
• Applications: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Notes: Small volumes of ADIPOR2 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ADIPOR2 adiponectin receptor 2 [ Homo sapiens ]
• Official Symbol: ADIPOR2
• Synonyms: ADIPOR2; adiponectin receptor 2; adiponectin receptor protein 2; ACDCR2; PAQR2; progestin and adipoQ receptor family member II; MGC4640; FLJ21432
• Gene ID: 79602
• mRNA Refseq: NM_024551
• Protein Refseq: NP_078827
• MIM: 607946
• UniProt ID: Q86V24
• Chromosome Location: 12p13
• Pathway: Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem
• Function: hormone binding; identical protein binding; protein heterodimerization activity; receptor activity