Recombinant Human Adiponectin, C1Q And Collagen Domain Containing

• Cat.No.: ADIPOQ-1849H
• Product Overview: Recombinant human ADIPOQcontains 145 amino acids corresponding to the C-terminal globular domain ofADIPOQ. It is expressed and secreted exclusively by adipose tissue.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: This protein possesses unique pharmacologicalproperties for regulation of body weight and lipid metabolism. It is a keycomponent in controlling energy homeostasis. Recently, ADIPOQ has been shownto inhibit the proliferation of myelomonocytic progenitors.
• Molecular Weight: 16.6 kDa
• Form: Lyophilized from 10mM Tris, pH 9.2 + 0.05% Sarcosyl + 0.75 mM DTT.
• Purity: > 98% asdetermined by SDS-PAGE analysis.
• Endotoxin Level: < 0.1 ng/µg ofADIPOQ
• Biological Activity: Determined by itsability to inhibit the proliferation of mouse myeloid cell lines M1. The ED50is < 1-3 µg/ml.
• Reconstitution: Centrifuge vialprior to opening. First add sterile distilled water to the vial to fully solubilizethe protein to a concentration of 1.0 mg/ml. After complete solubilization ofthe protein, it can be further diluted to other aqueous solutions.
• Storage: Store lyophilizedprotein at -20°C to -80°C. Reconstituted protein is stable for 1 week at2-4°Cor in working aliquots at -20°C for longer storage. Avoid repeatedfreeze-thaw cycles.
• OfficialSymbol: ADIPOQ

Gene Information

• Gene Name: ADIPOQ adiponectin, C1Q andcollagen domain containing [ Homo sapiens ]
• Synonyms: ADIPOQ; adiponectin,C1Q and collagen domain containing; ACDC; apM1; ADPN; APM1; APM-1; apM-1;GBP28; ACRP30; ADIPQTL1; adiponectin; AdipoQ; Gelatin-binding protein;OTTHUMP00000210047; OTTHUMP00000210048; gelatin-binding protein 28; adiposespecific collagen-like factor; 30 kDa adipocyte complement-related protein;adipocyte complement-related 30 kDa protein; adipose most abundant genetranscript 1 protein; adipocyte, C1Q and collagen domain containing
• Gene ID: 9370
• mRNA Refseq: NM_004797
• Protein Refseq: NP_004788
• MIM: 605441
• UniProt ID: Q15848
• Chromosome Location: 3q27
• Pathway: Adipocytokinesignaling pathway; Adipogenesis; Developmental Biology; PPAR signalingpathway; Transcriptional Regulation of White Adipocyte Differentiation; TypeII diabetes mellitus
• Function: cytokine activity;eukaryotic cell surface binding; hormone activity; identical protein binding;protein binding; protein homodimerization activity; receptor binding; sialicacid binding