Recombinant Human ADH1A Protein, His-tagged

• Cat.No.: ADH1A-343H
• Product Overview: Human ADH1A (NP_000658, 1 a.a. - 375 a.a.) full-length recombinant protein with His tag expressed in Escherichia coli.

Specification

• Description: This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid
• Molecular Mass: 42 kDa
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILMF
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Store at 4 centigrade for 1-2 weeks. For long term storage store at -20 centigrade or -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: 1 mg/mL
• Storage Buffer: In 20mM Tris-HCl, 100 mM NaCl, pH 8.0 (1 mM DTT, 10% glycerol)

Gene Information

• Gene Name: ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide [ Homo sapiens ]
• Official Symbol: ADH1A
• Synonyms: ADH1A; alcohol dehydrogenase 1A (class I), alpha polypeptide; ADH1; alcohol dehydrogenase 1A; ADH, alpha subunit; aldehyde reductase; alcohol dehydrogenase subunit alpha; alcohol dehydrogenase 1 (class I), alpha polypeptide
• Gene ID: 124
• mRNA Refseq: NM_000667
• Protein Refseq: NP_000658
• MIM: 103700
• UniProt ID: P07327