ADH1A
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Official Full Name
alcohol dehydrogenase 1A (class I), alpha polypeptide -
Overview
Human alcohol dehydrogenase (ADH) genes are grouped into five classes, with three distinct class I ADH genes (ADH1A, ADH1B and ADH1C) and ADH4, ADH5, ADH7 and ADH6 belonging to classes II, III, IV, and V, respectively. ADH is a zinc-containing, dimeric en -
Synonyms
ADH1A;alcohol dehydrogenase 1A (class I), alpha polypeptide;ADH1;alcohol dehydrogenase 1A;ADH, alpha subunit;aldehyde reductase;alcohol dehydrogenase subunit alpha;alcohol dehydrogenase 1 (class I), alpha polypeptide
Recombinant Proteins
- Human
- Rhesus macaque
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- HEK293T
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ADH1A involved in several pathways and played different roles in them. We selected most pathways ADH1A participated on our site, such as Abacavir metabolism,Abacavir transport and metabolism,Biological oxidations, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADH1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fatty Acid Omega Oxidation | CYP4A11,CYP2D6,ADH6,CYP2A6,ADH1C,ADH7,CYP2E1,CYP1A1,ADH1B,ADH4 |
| Ethanol oxidation | ADH1B,ADH8A,ADH7,ADH5,ADH6,ADH4,ADH8B,ADH1C |
| Fatty acid degradation | ACSL5,GCDHB,ACOX3,ACADSB,HADH,ALDH3A2A,ACAA1,ALDH9A1A.1,GCDHA,CYP4A11 |
| Drug metabolism - cytochrome P450 | ADH2-2,CYP2B6,GSTK1,ADH1B,CYP2C19,ADH7,ADH1C,CYP2C8,CYP3A5,CYP2E1 |
| Biological oxidations | CYP4F11,TPMT.2,AHCY,CYP2C18,CYP2K22,ACY3.2,CYP1A2,ACY3.1,CYP7A1,DPEP1 |
| Chemical carcinogenesis | ALDH3B1,ADH7,EPHX1,SULT1A1,AKR1C2,GSTM6,PTGS2,ALDH3B2,ADH2-1,CYP3A43 |
| Abacavir transport and metabolism | ADH8A,ADH8B,ADAL |
| Abacavir metabolism | ADH8B,ADH8A,ADAL |
Protein Function
ADH1A has several biochemical functions, for example, alcohol dehydrogenase (NAD) activity,alcohol dehydrogenase activity, zinc-dependent,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADH1A itself. We selected most functions ADH1A had, and list some proteins which have the same functions with ADH1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alcohol dehydrogenase (NAD) activity | ADH7,ADH6,ADH4,DHRS9,ADH1,ADH8B,ADH5,ADH1C,ADH8A |
| zinc ion binding | NEURL1AA,BARD1,PHEX,ISL1L,FAM90A1,ZNF385B,ZFP622,ZDHHC23,RANBP2,MMP2 |
| protein binding | COMTD1,CXorf40A,ANKRD49,IRAK1BP1,SLC22A17,ASCC1,RAB4A,TCEANC2,IL28RA,CD2 |
| alcohol dehydrogenase activity, zinc-dependent | ADH7,ADH4,ADH1B |
Interacting Protein
ADH1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADH1A here. Most of them are supplied by our site. Hope this information will be useful for your research of ADH1A.
CSNK2A2;HADH
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