Recombinant Human ADCY9, His-tagged

• Cat.No.: ADCY9-9411H
• Product Overview: Recombinant Human ADCY9 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 490-787a.a.
• Description: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ADCY9 adenylate cyclase 9 [ Homo sapiens ]
• Official Symbol: ADCY9
• Synonyms: ADCY9; adenylate cyclase 9; adenylate cyclase type 9; AC9; adenylyl cyclase 9; ATP pyrophosphate-lyase 9; adenylate cyclase type IX; type IX ATP pyrophosphate-lyase; FLJ12046
• Gene ID: 115
• mRNA Refseq: NM_001116
• Protein Refseq: NP_001107
• MIM: 603302
• UniProt ID: O60503
• Chromosome Location: 16p13.3
• Pathway: Activation of GABAB receptors, organism-specific biosystem; Adenylate cyclase activating pathway, organism-specific biosystem; Adenylate cyclase inhibitory pathway, organism-specific biosystem; Aquaporin-mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Ca-dependent events, organism-specific biosystem
• Function: ATP binding; GTPase activity; adenylate cyclase activity; metal ion binding; nucleotide binding