Recombinant Human ADCY8, His-tagged

• Cat.No.: ADCY8-3182H
• Product Overview: Adenylate cyclase type 8 (ADCY8), partial

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 1251
• Description: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of ADCY8 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ADCY8 adenylate cyclase 8 (brain) [ Homo sapiens ]
• Official Symbol: ADCY8
• Synonyms: ADCY8; adenylate cyclase 8 (brain); ADCY3; adenylate cyclase type 8; AC8; HBAC1; adenylyl cyclase 8; ATP pyrophosphate-lyase 8; adenylyl cyclase-8, brain; adenylate cyclase type VIII; ca(2+)/calmodulin-activated adenylyl cyclase
• Gene ID: 114
• mRNA Refseq: NM_001115
• Protein Refseq: NP_001106
• MIM: 103070
• UniProt ID: P40145
• Chromosome Location: 8q24
• Pathway: Activation of GABAB receptors, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Adenylate cyclase activating pathway, organism-specific biosystem; Adenylate cyclase inhib
• Function: ATP binding; GTPase activity; adenylate cyclase activity; calcium- and calmodulin-responsive adenylate cyclase activity; metal ion binding; nucleotide binding