Recombinant Human ADCY5 protein, His & T7-tagged

• Cat.No.: ADCY5-6927H
• Product Overview: Recombinant Human ADCY5 aa. (Gly167~Glu385 (Accession # O95622)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Gly167~Glu385
• Description: This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.2kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 7.0.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: ADCY5 adenylate cyclase 5 [ Homo sapiens (human) ]
• Official Symbol: ADCY5
• Synonyms: ADCY5; adenylate cyclase 5; AC5; FDFM; adenylate cyclase type 5; ATP pyrophosphate-lyase 5; adenylate cyclase type V; adenylyl cyclase 5
• Gene ID: 111
• mRNA Refseq: NM_001199642.1
• Protein Refseq: NP_001186571.1
• UniProt ID: O95622