Recombinant Human ADBR1 and GsαS fusion protein, Flag and His-tagged

• Cat.No.: ADRB1-1035H
• Product Overview: Recombinant full length Human ADBR1 Gly389 (aa1-477, P08588) with an N terminal FLAG tag fused at the C terminal to the N terminal of Gsαs (P63092-2) via a His tag, expressed in Sf9 insect cells; Predicted MWt 97 kDa.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Non
• Protein Length: 1-477 a.a.
• Description: The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
• Formulation: Liquid.
• Biologicalactivity: Receptor expression level: 2 - 10 pmol/mg
• Storage buffer: Preservative: None; Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
• OfficialSymbol: ADRB1
• Full Length: Full L.

Gene Information

• Gene Name: ADRB1 adrenoceptor beta 1 [ Homo sapiens ]
• Synonyms: adrenoceptor beta 1; ADRB1; RHR; B1AR; ADRB1R; BETA1AR; beta-1 adrenergic receptor; beta-1 adrenoceptor; beta-1 adrenoreceptor; adrenergic, beta-1-, receptor
• Gene ID: 153
• mRNA Refseq: NM_00068
• Protein Refseq: NP_000675
• UniProt ID: P08588
• Chromosome Location: 10q25.3
• Pathway: Adrenoceptors, organism-specific biosystem; Amine ligand-binding receptors, organism-specific biosystem ; Calcium Regulation in the Cardiac Cell, organism-specific biosystem
• Function: PDZ domain binding