Recombinant Human ADAR Protein, Thr30-Gln360, N-His tagged

• Cat.No.: ADAR-32H
• Product Overview: Purified recombinant protein of Human adenosine deaminase, RNA-specific (ADAR), transcript variant 4, Thr30-Gln360, with N-terminal His tag, expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: Thr30-Gln360
• Description: This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 36.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >0.05 μg/μL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol

Gene Information

• Gene Name: ADAR adenosine deaminase RNA specific [ Homo sapiens (human) ]
• Official Symbol: ADAR
• Synonyms: ADAR; adenosine deaminase RNA specific; DSH; AGS6; G1P1; IFI4; P136; ADAR1; DRADA; DSRAD; IFI-4; K88DSRBP; double-stranded RNA-specific adenosine deaminase; 136 kDa double-stranded RNA-binding protein; adenosine deaminase acting on RNA 1-A; dsRNA adenosine deaminase; dsRNA adeonosine deaminase; interferon-induced protein 4; interferon-inducible protein 4; EC 3.5.4.37
• Gene ID: 103
• mRNA Refseq: NM_001025107
• Protein Refseq: NP_001020278
• MIM: 146920
• UniProt ID: A0A7P0Z4F9