Recombinant Human ADAM28, His-tagged

Description :	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform. [provided by RefSeq, Jul 2008]
Source :	E. Coli
Species :	Human
Tag :	His
Form :	Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Molecular Mass :	29.3kDa
Protein length :	775
Endotoxin :	<1.0eu per 1ug (determined by the lal</1.0eu
Purity :	>95%
Applications :	SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
Notes :	Small volumes of ADAM28 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage :	Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
Reconstitution :	Reconstitute in sterile PBS, pH7.2-pH7.4.
Warning :	This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Name	ADAM28 ADAM metallopeptidase domain 28 [ Homo sapiens ]
Official Symbol	ADAM28
Synonyms	ADAM28; ADAM metallopeptidase domain 28; a disintegrin and metalloproteinase domain 28; disintegrin and metalloproteinase domain-containing protein 28; ADAM23; eMDCII; MDC Lm; MDC Ls; metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L; epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; MDCL; MDC-L; MDC-Lm; MDC-Ls; ADAM 28; eMDC II;
Gene ID	10863
mRNA Refseq	NM_014265
Protein Refseq	NP_055080
MIM	606188
UniProt ID	Q9UKQ2
Chromosome Location	8p21.2
Function	metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding;