Recombinant Human Acyl-CoA Thioesterase 13, His-tagged

• Cat.No.: ACOT13-2819H
• Product Overview: Recombinant human ACOT13, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 17.1 kDa (160aa), confirmed by MALDI-TOF.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Acyl-coenzyme A thioesterase 13, also known ACOT13, belongs to the thioesterase subfamily ofesterasefamily. Highly expressed in kidney with moderate expression in brain, liver and intestines, ACOT13 contains a hotdog-fold and is thought to co-localize with microtubules, possibly playing a role in cellular proliferation events. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus.
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MTSMTQSLRE VIKAMTKARN FERVLGKITL VSAAPGKVIC EMKVEEEHTN AIGTLHGGLT ATLVDNISTM ALLCTERGAP GVSVDMNITY MSPAKLGEDI VITAHVLKQG KTLAFTSVDL TNKATGKLIA QGRHTKHLGN
• Purity: > 95% by SDS – PAGE.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: ACOT13 acyl-CoA thioesterase 13 [ Homo sapiens ]
• Synonyms: ACOT13; acyl-CoA thioesterase 13; HT012; THEM2; MGC4961; PNAS-27; acyl-coenzyme A thioesterase 13; hypothalamus protein HT012; thioesterase superfamily member 2; EC 3.1.2.-
• Gene ID: 55856
• mRNA Refseq: NM_001160094
• Protein Refseq: NP_001153566
• UniProt ID: Q9NPJ3
• Chromosome Location: 6p22.3
• Function: acyl-CoA thioesterase activity; hydrolase activity