ACOT13
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Official Full Name
acyl-CoA thioesterase 13 -
Overview
This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ACOT13;acyl-CoA thioesterase 13;THEM2, thioesterase superfamily member 2;acyl-coenzyme A thioesterase 13;HT012;hypothalamus protein HT012;thioesterase superfamily member 2;THEM2;PNAS-27
Recombinant Proteins
- Rhesus macaque
- Human
- Zebrafish
- Mouse
- Mammalian Cell
- E.coli
- HEK293
- Mammalian cells
- HEK293T
- His
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
Involved Pathway
ACOT13 involved in several pathways and played different roles in them. We selected most pathways ACOT13 participated on our site, such as Fatty Acyl-CoA Biosynthesis,Fatty acid, triacylglycerol, and ketone body metabolism,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACOT13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fatty Acyl-CoA Biosynthesis | ACOT8,ELOVL1A,ACOT9,ACOT9.1,THEM5,ACOT11B,ACSF2,ACOT2,SLC25A1A,ACOT10 |
| Triglyceride Biosynthesis | DGAT1B,ACOT11A,TMEM195,ACOT9.2,ACOT6,ACOT11,ACOT10,ACOT11B,ELOVL1A,SLC25A1A |
| Metabolism | OSBP,ARSI,CYP2R1,MARCKSB,NUDT18,COX6B1,LOC100686744,CETP,SLC25A20,LMF2 |
| Metabolism of lipids and lipoproteins | SLC27A5,CYP27B1,FIG4,AKR1C4,ACOT11A,FABP11A,GRHL1,HSD17B11,DHCR24,PIK3R6 |
| Fatty acid, triacylglycerol, and ketone body metabolism | MED15,CPT1B,PLIN2,MED20,MED26,ESRRA,CYP4A11,MED25,APOA5,MED10 |
Protein Function
ACOT13 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ACOT13 itself. We selected most functions ACOT13 had, and list some proteins which have the same functions with ACOT13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
ACOT13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACOT13 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACOT13.
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References
- Yamada, J; Kuramochi, Y; et al. Human brain acyl-CoA hydrolase isoforms encoded by a single gene. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 299:49-56(2002).
