Recombinant Human ACY3, His-tagged

• Cat.No.: ACY3-26720TH
• Product Overview: Recombinant full length Human ACY3 with an N terminal His tag; 342 amino acids with tag, Predicted MWt 37.6 kDa.

Specification

• Description: Plays an important role in deacetylating mercapturic acids in kidney proximal tubules.
• Protein length: 319 amino acids
• Conjugation: HIS
• Molecular Weight: 37.600kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGSMCSLPVPREPLRRVAVTGGTHGNEMSGVYLARHWLHAPAELQRASFSAVPVLANPAATSGCRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLLGPKASGQAFDFVLDLHNTTANMGTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFLYQRSGEESYNLDSVAKNGLGLELGPQPQGVLRADIFSRMRTLVATVLDFIELFNQGTAFPAFEMEAYRPVGVVDFPRTEAGHLAGTVHPQLQDRDFQPLQPGAPIFQMFSGEDLLYEGESTVYPVFINEAAYYEKGVAFVQTEKFTFTVPAMPALTPAPSPAS
• Sequence Similarities: Belongs to the AspA/AstE family. Aspartoacylase subfamily.

Gene Information

• Gene Name: ACY3 aspartoacylase (aminocyclase) 3 [ Homo sapiens ]
• Official Symbol: ACY3
• Synonyms: ACY3; aspartoacylase (aminocyclase) 3; aspartoacylase-2; ACY 3; HCBP1; MGC9740
• Gene ID: 91703
• mRNA Refseq: NM_080658
• Protein Refseq: NP_542389
• Uniprot ID: Q96HD9
• Chromosome Location: 11q13
• Pathway: Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Histidine metabolism, organism-specific biosystem; Histidine metabolism, conserved biosystem
• Function: aminoacylase activity; hydrolase activity, acting on ester bonds; identical protein binding; metal ion binding