ACY3
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Official Full Name
aspartoacylase (aminocyclase) 3 -
Overview
Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. -
Synonyms
ACY3;aspartoacylase (aminocyclase) 3;aspartoacylase-2;ACY 3;HCBP1;MGC9740;0610006H10Rik;AA3;ACY-3;ACY3_HUMAN;Acylase III;Aminoacylase 3;Aminoacylase III;Aminoacylase-3;ASPA2;Aspartoacylase (aminoacylase) 3;Aspartoacylase 2;AW107362;EC 3.5.1.-;EC 3.5.1.15;Hepatitis C virus core binding protein 1;Hepatitis C virus core-binding protein 1;MGC108859;RGD1305394;OTTHUMP00000235614;OTTHUMP00000235615
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Myc&DDK
- Non
- His&Fc&Avi
Involved Pathway
ACY3 involved in several pathways and played different roles in them. We selected most pathways ACY3 participated on our site, such as Aflatoxin activation and detoxification,Biological oxidations,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACY3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biological oxidations | CYP4F12,CYP2J2,CYP2K8,ACY3.2,SULT1C2,FDX1,CYP1A1,FAM84B,COMT,SLC26A2 |
| Metabolism | CYP51A1,KCNB1,NDUFAF4,NUDT5,SLC4A1A,NOSTRIN,FABP12,ELA2,PTPMT1,PPARGC1B |
| Aflatoxin activation and detoxification | CYP3A4,PRKRA,FAM84B,CYP1A2,CYP2A13,DPEP2,CYP3A5,ACY3.2,CYP2Y3,DPEP1 |
Protein Function
ACY3 has several biochemical functions, for example, aminoacylase activity,hydrolase activity, acting on ester bonds,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACY3 itself. We selected most functions ACY3 had, and list some proteins which have the same functions with ACY3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PIR,SHARPIN,BMP7,CLASP1,NEURL1B,NAT10,GAPDHS,ARMC9,FOXO3,DLGAP1 |
| hydrolase activity, acting on ester bonds | ENDOU2,ACY3.2,SMFN,LIPM,LIPN,ESD,ACY3.1,PTER,IAH1,PGAP3 |
| identical protein binding | CEACAM16,ALDH4A1,PCM1,SNX8,WAS,DIAP1,ADIPOR1,HCFC1,GPSM2,PRKAB2 |
| molecular_function | SMU1A,TMEM110,DDX26B,ABTB2,CCDC114,TMEM117,CTXN2,PDAP1B,FAM40A,FGFBP2B |
| aminoacylase activity | DARS,ACY1,CAT,ASPA |
| metal ion binding | THAP8,Car8,STK32B,ATP12A,CYB5D1,COQ7,ZMYND15,HEPHL1A,ARFGAP1,KLF10 |
Interacting Protein
ACY3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACY3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACY3.
GORASP2;PMM2;PIAS2;ASPA;NOTCH2NL
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References
- Hiltunen, TP; Donner, KM; et al. Pharmacogenomics of Hypertension: A Genome-Wide, Placebo-Controlled Cross-Over Study, Using Four Classes of Antihypertensive Drugs. JOURNAL OF THE AMERICAN HEART ASSOCIATION 4:-(2015).
- Rise, ML; Nash, GW; et al. Variation in embryonic mortality and maternal transcript expression among Atlantic cod (Gadus morhua) broodstock: A functional genomics study. MARINE GENOMICS 18:3-20(2014).
