Recombinant Human ACVR2B Protein, MYC/DDK-tagged
Cat.No. : | ACVR2B-1155H |
Product Overview : | Recombinant human ACVR2B protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Protein Length : | Full Length |
Description : | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008] |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 57.5 kDa |
Purity : | >50 ug/mL as determined by microplate BCA method |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name | ACVR2B activin A receptor, type IIB [ Homo sapiens ] |
Official Symbol | ACVR2B |
Synonyms | ActR-IIB; ACTRIIB; HTX4 |
Gene ID | 93 |
mRNA Refseq | NM_001106 |
Protein Refseq | NP_001097 |
MIM | 602730 |
UniProt ID | Q13705 |
◆ Recombinant Proteins | ||
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Acvr2b-529M | Recombinant Mouse Acvr2b Protein, MYC/DDK-tagged | +Inquiry |
ACVR2B-197H | Recombinant Human ACVR2B protein(Met1-Thr134), His-tagged | +Inquiry |
ACVR2B-1586H | Recombinant Human Activin A Receptor, Type IIB | +Inquiry |
ACVR2B-2182C | Active Recombinant Cynomolgus ACVR2B protein, hFc-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
ACVR2B-734CCL | Recombinant Cynomolgus ACVR2B cell lysate | +Inquiry |
ACVR2B-2724HCL | Recombinant Human ACVR2B cell lysate | +Inquiry |
ACVR2B-2540MCL | Recombinant Mouse ACVR2B cell lysate | +Inquiry |
Not For Human Consumption!
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08/28/2024
I appreciate the care with which you are producing the proteins. It increases my confidence in recommending Creative-Biomart to my colleagues.
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