Recombinant Human ACVR2A Protein, His/GST-tagged
| Cat.No. : | ACVR2A-292H |
| Product Overview : | Recombinant Human ACVR2A(Ala20~Pro135) fused with His/GST tag at N-terminal was expressed in E. coli. |
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| Description : | This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. |
| Source : | E.coli |
| Species : | Human |
| Tag : | His&GST |
| Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| Molecular Mass : | 40.5kDa |
| Protein length : | Ala20~Pro135 |
| Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
| Purity : | > 95% |
| Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
| Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
| Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
| Reconstitution : | Reconstitute in PBS or others |
| Gene Name | ACVR2A activin A receptor, type IIA [ Homo sapiens ] |
| Official Symbol | ACVR2A |
| Synonyms | ACVR2A; activin A receptor, type IIA; activin A receptor, type II , ACVR2; activin receptor type-2A; ACTRII; ACVR2; |
| Gene ID | 92 |
| mRNA Refseq | NM_001616 |
| Protein Refseq | NP_001607 |
| MIM | 102581 |
| UniProt ID | P27037 |
Not For Human Consumption!
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