Recombinant Human Activin A Receptor, Type I

Cat. No. :	ACVR1-2743H
Description :	Activins are homodimers or heterodimers of the various b subunit isoforms, belonging to the TGFb family. Mature Activin a has two 116 amino acids residues βA subunits (βA - βA). Activin exhibits a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins plays a key role in the production and regulation of hormones such as FSH, LH, GnRH and ACTH.
Source :	Nicotiana benthamiana.
MW :	recombinant protein βA chain, monomeric form 14.54 kDa containing 116 amino acid residues.
Endotoxin Level :	< 0.04 EU/ μg protein (LAL method).
Formulation :	Lyophilized from a buffer of Tris HCl 0.05M pH 7.4.
Storage :	This lyophilized preparation is stable at 2-8⁰C, but should be kept at –20⁰C for long termstorage. Repeated freezing and thawing is not recommended.
Tag :	Non

Gene Name	ACVR1 activin A receptor, type I [ Homo sapiens ]
Synonyms	ACVR1; activin A receptor, type I; OTTHUMP00000204604; OTTHUMP00000204626; TGF-B superfamily receptor type I; activin A receptor, type II-like kinase 2; activin receptor type I; activin receptor type-1; activin receptor-like kinase 2; hydroxyalkyl-protein kinase; serine/threonine-protein kinase receptor R1; EC 2.7.11.30
Gene ID	90
mRNA Refseq	NM_001105
Protein Refseq	NP_001096
MIM	102576
UniProt ID	Q04771
Chromosome Location	2q23-q24
Pathway	Cytokine-cytokine receptor interaction; TGF-beta signaling pathway
Function	ATP binding; contributes_to activin receptor activity, type I; transmembrane receptor protein serine/threonine kinase activity; transforming growth factor beta binding; protein homodimerization activity