Recombinant Human acid phosphatase, prostate Protein, His&Flag tagged

• Cat.No.: ACPP-222H
• Product Overview: Recombinant human ACP3/ACPP protein (P15309-1) (Lys 33-Gln 379) with both His, Flag tag at the C-terminus was expressed in HEK293.

Specification

• Description: This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
• Source: HEK293
• Species: Human
• Tag: C-His&Flag
• Protein length: 33-379aa
• Molecular Mass: 43 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: ACPP acid phosphatase, prostate [ Homo sapiens (human) ]
• Official Symbol: ACPP
• Synonyms: ACPP; acid phosphatase, prostate; prostatic acid phosphatase; ACP 3; ACP3; TMPase; 5-nucleotidase; ecto-5-nucleotidase; thiamine monophosphatase; prostatic acid phosphotase; PAP; 5-NT; ACP-3
• Gene ID: 55
• mRNA Refseq: NM_001099
• Protein Refseq: NP_001090
• MIM: 171790
• UniProt ID: P15309