Recombinant Human ACE2 protein, His/Avi-tagged

• Cat.No.: ACE2-229H
• Product Overview: Recombinant Human ACE2 protein (Gln18- Ser740) was expressed from mammalian with a His tag and Avi at the C-terminal.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Avi&His
• Protein Length: 723
• Description: ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension. The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7.
• Form: Supplied as 0.22μm filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 86.5 kDa. Due to glycosylation, the protein migrates to 95-110 kDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 1 EU per μg by the LAL method.
• Purity: >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC.
• Storage: The product should be stored at -70 centigrade. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
• Warning: For Research Use Only.

Gene Information

• Gene Name: ACE2
• Official Symbol: ACE2
• Synonyms: ACEH
• Gene ID: 59272
• mRNA Refseq: NM_021804.3
• Protein Refseq: NP_068576.1
• MIM: 300335
• UniProt ID: Q9BYF1