Recombinant Human ACE2 Protein

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Cat.No Protein Length MW DataSheet
ACE2-0048H Datasheet
ACE2-2413H-B Datasheet
ACE2-2012M Gln 18 - Ser 740 Datasheet

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Cat.No. Purity Endotoxin Bio-activity Applications
ACE2-0048H
ACE2-2413H-B Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
ACE2-2012M Immobilized 15 μg ACE2 protein to 1 mg Beads, can bind the SARS-CoV-2 S1 protein, Fc Tag with an EC50 of 1.402 μg/mL.
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  • Gene Information
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Species : Human
Source : HEK293
Description : The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible.
Notes : For research use only, not for use in diagnostic procedure.
Storage : Short term (up to 7 days) store at 2–8 centigrade. Long term, store at - 20 centigrade. Avoid multiple freeze/thaw cycles.
Storage Buffer : Supplied as a 0.2 μm filtered solution of PBS, pH7.4
Gene Name ACE2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [ Homo sapiens (human) ]
Official Symbol ACE2
Synonyms ACE2; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2; metalloprotease MPROT15; ACE-related carboxypeptidase; angiotensin I converting enzyme 2; angiotensin-converting enzyme homolog; ACEH;
Gene ID 59272
mRNA Refseq NM_021804
Protein Refseq NP_068576
MIM 300335
UniProt ID Q9BYF1

Not For Human Consumption!

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