Recombinant Human ACE2 Protein
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Cat.No. | Purity | Endotoxin | Bio-activity | Applications |
---|---|---|---|---|
ACE2-0048H | ||||
ACE2-2413H-B | Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification. | |||
ACE2-2012M | Immobilized 15 μg ACE2 protein to 1 mg Beads, can bind the SARS-CoV-2 S1 protein, Fc Tag with an EC50 of 1.402 μg/mL. |
- Specification
- Gene Information
- Related Products
Species : | Human |
Source : | HEK293 |
Description : | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible. |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Short term (up to 7 days) store at 2–8 centigrade. Long term, store at - 20 centigrade. Avoid multiple freeze/thaw cycles. |
Storage Buffer : | Supplied as a 0.2 μm filtered solution of PBS, pH7.4 |
Gene Name | ACE2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [ Homo sapiens (human) ] |
Official Symbol | ACE2 |
Synonyms | ACE2; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2; metalloprotease MPROT15; ACE-related carboxypeptidase; angiotensin I converting enzyme 2; angiotensin-converting enzyme homolog; ACEH; |
Gene ID | 59272 |
mRNA Refseq | NM_021804 |
Protein Refseq | NP_068576 |
MIM | 300335 |
UniProt ID | Q9BYF1 |
◆ Recombinant Proteins | ||
ACE2-009H | Active Recombinant Human ACE2 protein, Fc-tagged | +Inquiry |
ACE2-108C | Recombinant Cynomolgus ACE2 protein, His-tagged | +Inquiry |
ACE2-052H | Active Recombinant Human ACE2 protein, Fc/Avi-tagged, Biotinylated | +Inquiry |
Ace2-1184M | Recombinant Mouse ACE2 protein(Met1-Thr740), His-tagged | +Inquiry |
ACE2-2186H | Active Recombinant Human ACE2 protein, mFc-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
ACE2-887CCL | Recombinant Cynomolgus ACE2 cell lysate | +Inquiry |
ACE2-3100HCL | Recombinant Human ACE2 cell lysate | +Inquiry |
ACE2-2085MCL | Recombinant Mouse ACE2 cell lysate | +Inquiry |
ACE2-1851RCL | Recombinant Rat ACE2 cell lysate | +Inquiry |
Not For Human Consumption!
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