Recombinant Human ACADM Protein, GST-Tagged

• Cat.No.: ACADM-133H
• Product Overview: Recombinant Human ACADM Protein, GST-Tagged was expressed in Wheat Germ cell

Specification

• Description: This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: Wheat Germ (in vitro)
• Species: Human
• Tag: GST
• Molecular Mass: 73kDa
• AA Sequence: MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYKN
• Applications: Enzyme-linked Immunoabsorbent Assay. Western Blot (Recombinant protein). Antibody Production. Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Preparation: Glutathione Sepharose 4 Fast Flow

Gene Information

• Gene Name: ACADM acyl-CoA dehydrogenase medium chain [ Homo sapiens (human) ]
• Official Symbol: ACADM
• Synonyms: ACAD1,FLJ18227,FLJ93013,FLJ99884,MCAD,MCADH
• Gene ID: 34
• mRNA Refseq: NM_000016.6
• Protein Refseq: NP_000007.1
• MIM: 607008
• UniProt ID: P11310