Recombinant Human ABP1, His-tagged

• Cat.No.: ABP1-3409H
• Product Overview: Amiloride-sensitive amine oxidase [copper-containing] (ABP1)

Specification

• Description: This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 751
• Purity: >90%
• Notes: Small volumes of ABP1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ABP1 amiloride binding protein 1 (amine oxidase (copper-containing)) [ Homo sapiens ]
• Official Symbol: ABP1
• Synonyms: ABP1; amiloride binding protein 1 (amine oxidase (copper-containing)); amiloride-sensitive amine oxidase [copper-containing]; AOC1; DAO; histaminase; diamine oxidase; kidney amine oxidase; amiloride-binding protein-1; amiloride-sensitive amine oxidase; ABP; KAO; DAO1
• Gene ID: 26
• mRNA Refseq: NM_001091
• Protein Refseq: NP_001082
• MIM: 104610
• UniProt ID: P19801
• Chromosome Location: 7q34-qter
• Pathway: Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Histidine metabolism, organism-specific biosystem; Histidine metabolism, conserved biosystem; Tryptophan metabolism, organism-specific bios
• Function: calcium ion binding; cation channel activity; copper ion binding; diamine oxidase activity; drug binding; heparin binding; histamine oxidase activity; methylputrescine oxidase activity; oxidoreductase activity; primary amine oxidase activity; propane-1,3-diamine oxidase activity; protein complex binding; protein homodimerization activity; quinone binding; receptor activity; sodium channel activity; zinc ion binding