Recombinant Human ABCC9, His-tagged

• Cat.No.: ABCC9-3732H
• Product Overview: ATP-binding cassette sub-family C member 9 (ABCC9), partial

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 1549
• Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of ABCC9 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ABCC9
• Official Symbol: ABCC9
• Synonyms: ABCC9; SUR2 ; ABCC9; ABCC9; SUR2; ABC37;...
• Gene ID: 10060
• mRNA Refseq: NM_005691.2
• Protein Refseq: NP_005682.2
• MIM: 239850
• UniProt ID: O60706
• Chromosome Location: Chromosome: 12; NC_000012.11 (21950323..22089628, complement). Location: 12p12.1
• Function: ?the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O