Recombinant Human ABCB9, GST-tagged

• Cat.No.: ABCB9-9213H
• Product Overview: Recombinant human ABCB9 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 36-181a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 [ Homo sapiens ]
• Official Symbol: ABCB9
• Synonyms: ABCB9; ATP-binding cassette, sub-family B (MDR/TAP), member 9; ATP-binding cassette sub-family B member 9; EST122234; TAP-like protein; ABC transporter 9 protein; TAPL; KIAA1520
• Gene ID: 23457
• mRNA Refseq: NM_001243013
• Protein Refseq: NP_001229942
• MIM: 605453
• UniProt ID: Q9NP78
• Chromosome Location: 12q24
• Pathway: ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem
• Function: ATP binding; ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; MHC class I protein binding; TAP1 binding; TAP2 binding; nucleotide binding; oligopeptide-transporting ATPase activity; peptide antigen binding; p