ABCB9
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Official Full Name
ATP-binding cassette, sub-family B (MDR/TAP), member 9 -
Overview
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities. -
Synonyms
ABCB9;ATP-binding cassette, sub-family B (MDR/TAP), member 9;ATP-binding cassette sub-family B member 9;EST122234;TAP-like protein;ABC transporter 9 protein;TAPL;KIAA1520
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- GST
- His
- His&T7
- Non
- His&Fc&Avi
Involved Pathway
ABCB9 involved in several pathways and played different roles in them. We selected most pathways ABCB9 participated on our site, such as ABC transporters,Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCB9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | CTSBA,ARSB,ARSG,SORT1,CD63,GUSB,GALCB,AP3S2,ASAH1,HEXA |
| ABC transporters | ABCA5,TAP1,ABCB5,ABCC2,ABCB6A,ABCB1LB,ABCA3,ABCC6,Abca2,ABCB7 |
Protein Function
ABCB9 has several biochemical functions, for example, ATP binding,oligopeptide-transporting ATPase activity,peptide-transporting ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCB9 itself. We selected most functions ABCB9 had, and list some proteins which have the same functions with ABCB9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CUTA,CCDC92,SP2,SSX1,KLK13,SYNPO2L,RYR1B,PIH1D3,ZBP1,ATP6AP2 |
| substrate-specific transmembrane transporter activity | SLC2A12,SLC2A13,SLC2A11B,SLC2A11L,SLC2A1A,SVOP,SLC2A15A,SLC2A7,HIAT1B,SLC2A8 |
| ATP binding | PEBP1,ERCC6L2,MLKL,FGFR1A,DCK,MAT2AL,ROCK1,CHEK1,SRMS,MKKS |
| protein homodimerization activity | CD247,JUP,BNIP3,ERN1,ECT2,ADIPOQ,PDZD7,HEYL,CCDC103,VEGFA |
| peptide-transporting ATPase activity | TAP1 |
Interacting Protein
ABCB9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCB9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCB9.
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References
- Wong, LJC; Dimmock, D; et al. Utility of oligonucleotide array-based comparative genomic hybridization for detection of target gene deletions. CLINICAL CHEMISTRY 54:1141-1148(2008).
