Recombinant Human ABCA2 protein, His-tagged

• Cat.No.: ABCA2-13H
• Product Overview: Recombinant Human ABCA2(Leu2201~Cys2436) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 30.4kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.
• Protein length: 2201-2436 a.a.

Gene Information

• Gene Name: ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 [ Homo sapiens ]
• Official Symbol: ABCA2
• Synonyms: ABCA2; ATP-binding cassette, sub-family A (ABC1), member 2; ABC2; ATP-binding cassette sub-family A member 2; ATP-binding cassette 2; ATP-binding cassette transporter 2; ATP-binding cassette, sub-family A, member 2; MGC129761
• Gene ID: 20
• mRNA Refseq: NM_001606
• Protein Refseq: NP_001597
• MIM: 600047
• UniProt ID: Q9BZC7