Recombinant HLA-A*0201 WT-1 (RMFPNAPYL) complex protein, His-Avi-tagged

• Cat.No.: HLA-A-068H
• Product Overview: Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is expressed from mammalian with a His and avi tag at the C-terminal. It contains Gly 25 - Thr 305 (HLA-A*0201),Ile21-Met119 (B2M) and RMFPNAPYL peptide design

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: It contains Gly 25 - Thr 305 (HLA-A*0201),Ile21-Met119 (B2M) and RMFPNAPYL peptide design
• Description: The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein has a calculated MW of 50.5kDa. The protein migrates as 50-60 kDa under reducing (R) condition (Bis-Tris PAGE) .
• Endotoxin: Less than 0.001EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: HLA-A major histocompatibility complex, class I, A [ Homo sapiens ]
• Official Symbol: HLA-A
• Synonyms: MHC, WT1, RMF, Wilms tumor protein
• Gene ID: 3105
• mRNA Refseq: NM_001242758
• Protein Refseq: NP_001229687
• UniProt ID: P01891