Recombinant HIV-1 [Group O] gp41 protein, his-tagged

• Cat.No.: gp41-10H
• Product Overview: Recombinant HIV-1 [Group O] gp41 protein with a His tag was expressed in E. coli.

Specification

• Species: HIV
• Source: E.coli
• Tag: His
• Description: gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
• Molecular Mass: 13 kDa
• Purity: ~ 95% by SDS-PAGE
• Applications: ELISA, western blot, lateral flow immunoassay
• Storage: Aliquot & freeze (≤ -20 centigrade)
• Storage Buffer: 20 mM Na-carbonate, pH9.6

Gene Information

• Synonyms: Env; Glycoprotein 41; gp41; Human Immunodeficiency Virus 1; TM; Transmembrane protein