Recombinant Full Length Mouse Ppp2r1a Protein, Myc/DDK-tagged

• Cat.No.: Ppp2r1a-5078M
• Product Overview: Purified recombinant protein of mouse full-length protein phosphatase 2, regulatory subunit A, alpha (Ppp2r1a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis.
• Molecular Mass: 65.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ppp2r1a protein phosphatase 2, regulatory subunit A, alpha [ Mus musculus (house mouse) ]
• Official Symbol: Ppp2r1a
• Synonyms: PPP2R1A; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; protein phosphatase PP2A; PP2A subunit A isoform R1-alpha; PP2A subunit A isoform PR65-alpha; serine/threonine protein phosphatase A subunit type 2A; PP2A; PR65; 6330556D22Rik
• Gene ID: 51792
• mRNA Refseq: NM_016891
• Protein Refseq: NP_058587
• UniProt ID: Q76MZ3