Recombinant Full Length Mouse Ppp2r1a Protein (Met1-Ala589), C-His tagged

• Cat.No.: Ppp2r1a-6778M
• Product Overview: Recombinant mouse Ppp2r1a (Met1-Ala589) fused with the C-terminal His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Met1-Ala589
• Description: Enables protein serine/threonine phosphatase activity. Acts upstream of or within several processes, including nuclear division; peptidyl-serine dephosphorylation; and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Located in cytosol and glutamatergic synapse. Part of protein phosphatase type 2A complex. Is active in synapse. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog (s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 36. Orthologous to human PPP2R1A (protein phosphatase 2 scaffold subunit Aalpha).
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 65.79 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Ppp2r1a protein phosphatase 2, regulatory subunit A, alpha [ Mus musculus (house mouse) ]
• Official Symbol: Ppp2r1a
• Synonyms: PPP2R1A; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform, protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; PP2A Aalpha; PR65A; protein phosphatase 2; 65kDa regulatory subunit A; protein phosphatase 2A; regulatory subunit A; alpha isoform; PP2A subunit A isoform R1-alpha; PP2A subunit A isoform PR65-alpha; medium tumor antigen-associated 61 KDA protein; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform; PP2AAALPHA; MGC786; PP2A-Aalpha
• Gene ID: 51792
• mRNA Refseq: NM_016891
• Protein Refseq: NP_058587
• UniProt ID: Q76MZ3