Recombinant Full Length Human Stanniocalcin 2, T7-tagged

• Cat.No.: STC2-201H
• Product Overview: Recombinant Human STC2 (1-302 aa) is expressed in E.Coli with a T7 tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-302 a.a.
• Description: STC2 is a homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive over expression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
• MW: 33249 Da.
• Purity: 90%.
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. 10mM DTT.
• Application: MS. SDS.

Gene Information

• Gene Name: STC2 stanniocalcin 2 [ Homo sapiens ]
• Synonyms: STC2; stanniocalcin 2; STC-2; STCRP; STC-related protein; stanniocalcin-related protein; Stanniocalcin-2; Stanniocalcin-related protein
• Gene ID: 8614
• mRNA Refseq: NM_003714
• Protein Refseq: NP_003705
• MIM: 603665
• UniProt ID: O76061
• Chromosome Location: 5q35.2
• Function: hormone activity