Recombinant Full Length Human SP1 Protein, N-His-tagged

• Cat.No.: SP1-98HFL
• Product Overview: Recombinant Full Length Human SP1 Protein, fused to His-tag at N-terminus, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
• Form: 50mM Tris, 8M Urea, pH8.0.
• Molecular Mass: 80.5 kDa
• AA Sequence: A DNA sequence encoding human full-length SP1.
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
• Protein Pathways: Huntington's disease, TGF-beta signaling pathway
• Full Length: Full L.

Gene Information

• Gene Name: SP1 Sp1 transcription factor [ Homo sapiens (human) ]
• Official Symbol: SP1
• Synonyms: Sp1 transcription factor; specificity protein 1
• Gene ID: 6667
• mRNA Refseq: NM_138473.3
• Protein Refseq: NP_612482.2
• MIM: 189906
• UniProt ID: P08047