Recombinant Full Length Human PTPN6 Protein (M1-K595), His/Strep tagged

• Cat.No.: PTPN6-0698H
• Product Overview: Recombinant Human 6His-strepII-TEV-GG-PTPN6(M1-K595 end) Protein was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&Strep
• Protein Length: M1-K595
• Description: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
• Form: Liquid
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: PTPN6 protein tyrosine phosphatase, non-receptor type 6 [ Homo sapiens (human) ]
• Official Symbol: PTPN6
• Synonyms: PTPN6; protein tyrosine phosphatase, non-receptor type 6; tyrosine-protein phosphatase non-receptor type 6; HCP; HCPH; PTP 1C; SHP 1; SHP1; hematopoietic cell phosphatase; protein-tyrosine phosphatase 1C; protein-tyrosine phosphatase SHP-1; hematopoietic cell protein-tyrosine phosphatase; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1
• Gene ID: 5777
• mRNA Refseq: NM_002831
• Protein Refseq: NP_002822
• MIM: 176883
• UniProt ID: P29350