Recombinant Full Length Human PDZK1 Protein
Cat.No. : | PDZK1-368HF |
Product Overview : | Recombinant full length Human PDZK1 with N terminal proprietary tag; Predicted MWt 83.2 kDa. |
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Species : | Human |
Source : | In Vitro Cell Free System |
Protein Length : | 519 amino acids |
Description : | This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Form : | Liquid |
Molecular Mass : | 83.200kDa inclusive of tags |
AA Sequence : | MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEK CSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLVRKSGN SVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILS PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYM TDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKV KKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQ PRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEA GLKNNDLVVAVNGESVETLDHDSVVEMIRKGGDQTSLLVV DKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSL EVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPG SFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVV DRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDT PPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM |
Purity : | Proprietary Purification |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
Storage Buffer : | pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
Gene Name | PDZK1 PDZ domain containing 1 [ Homo sapiens ] |
Official Symbol | PDZK1 |
Synonyms | PDZK1; PDZ domain containing 1; Na(+)/H(+) exchange regulatory cofactor NHE-RF3; NHERF3; PDZD1 |
Gene ID | 5174 |
mRNA Refseq | NM_001201325 |
Protein Refseq | NP_001188254 |
MIM | 603831 |
UniProt ID | Q5T2W1 |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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