Recombinant Full Length Human PCM1 Protein

• Cat.No.: PCM1-362HF
• Product Overview: Recombinant full length Human PCM1 with N terminal proprietary tag, predicted mwt: 84.41 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• ProteinLength: 530 amino acids
• Description: The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma.
• Form: Liquid
• Molecular Mass: 84.410kDa inclusive of tags
• AA Sequence: MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKK ANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTP HTFPHSRYMSQMSVPEQAELEKLKQRINFSDLDQRSIGSD SQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTSP PNRETIGSAQCKELFASALSNDLLQNCQVSEEDGRGEPAM ESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLT HLIDHLKEQEKSYMKFLKKILARENEEEDVRTIDSAVGSG SVAESTSLNIDVQSEASDTTARDPQQEPMEEIENLKKQHD LLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSV VAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPAV PDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMR VLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRST SAPSASVGLAPVVNGESNSLTSSVPYPTASLVSQNESENE GHLNPSEKLQ
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: PCM1 pericentriolar material 1 [ Homo sapiens ]
• Official Symbol: PCM1
• Synonyms: PCM1; pericentriolar material 1; pericentriolar material 1 protein; PTC4
• Gene ID: 5108
• mRNA Refseq: NM_006197
• Protein Refseq: NP_006188
• MIM: 600299
• UniProt ID: Q15154