Recombinant Full Length Human NCBP1 Protein

• Cat.No.: NCBP1-332HF
• Product Overview: Recombinant full length Human NCBP1 with N terminal proprietary tag; Predicted MW 112.64 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 790 amino acids
• Description: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5 cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.
• Form: Liquid
• Molecular Mass: 112.640kDa inclusive of tags
• AA Sequence: MSRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGE KSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLP EKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN YNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEED VPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTE SYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLK KDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDS VYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHC IIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELF QLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYM RLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQD PESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPAN PTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSI LKDVPNPNQDDDDDEGFSFNPLKIEVFVQTLLHLAAKSFS HSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQM IAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEI LHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRS SDRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMI LTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQ YMVTLENLLFTAELDPHILAVFQQFCALQA
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: NCBP1 nuclear cap binding protein subunit 1, 80kDa [ Homo sapiens ]
• Official Symbol: NCBP1
• Synonyms: NCBP1; nuclear cap binding protein subunit 1, 80kDa; NCBP, nuclear cap binding protein subunit 1, 80kD; nuclear cap-binding protein subunit 1; CBP80; Sto1
• Gene ID: 4686
• mRNA Refseq: NM_002486
• Protein Refseq: NP_002477
• MIM: 600469
• UniProt ID: Q09161