NCBP1

  • Official Full Name

    nuclear cap binding protein subunit 1, 80kDa

  • Overview

    The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5 cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.

  • Synonyms

    NCBP1;nuclear cap binding protein subunit 1, 80kDa;NCBP, nuclear cap binding protein subunit 1, 80kD;nuclear cap-binding protein subunit 1;CBP80;Sto1;NCBP 80 kDa subunit;80 kDa nuclear cap-binding protein;NCBP;MGC2087

Recombinant Proteins

  • Mouse
  • Human
  • Chicken
  • Rat
  • Mammalian Cell
  • Wheat Germ
  • E.coli
  • Insect Cell
  • HEK293
  • Mammalian cells
  • In Vitro Cell Free System
  • HEK293T
  • His
  • Non
  • His&Myc
  • Myc&DDK
  • Flag
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
NCBP1-10462M Recombinant Mouse NCBP1 Protein Mammalian Cell Mouse His
NCBP1-27855TH Recombinant Human NCBP1 Wheat Germ Human Non 790 amino acids
NCBP1-29240TH Recombinant Human NCBP1 Wheat Germ Human Non 790 amino acids
NCBP1-29294TH Recombinant Human NCBP1 Wheat Germ Human Non 98 amino acids
NCBP1-3088C Recombinant Chicken NCBP1 Mammalian Cell Chicken His
NCBP1-3917R Recombinant Rat NCBP1 Protein Mammalian Cell Rat His
NCBP1-1171HCL Recombinant Human NCBP1 cell lysate Human Non
NCBP1-1228H Recombinant Human NCBP1 protein, His&Myc-tagged E.coli Human His&Myc 1-790aa
NCBP1-1290H Recombinant Human NCBP1 protein, His&Myc-tagged Insect Cell Human His&Myc 1-790aa
NCBP1-131H Recombinant Human NCBP1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK
NCBP1-1356HFL Recombinant Full Length Human NCBP1 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
NCBP1-1484H Recombinant Human NCBP1 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
NCBP1-1484H-B Recombinant Human NCBP1 Protein Pre-coupled Magnetic Beads HEK293 Human
NCBP1-332HF Recombinant Full Length Human NCBP1 Protein In Vitro Cell Free System Human Full L. 790 amino acids
NCBP1-3575R Recombinant Rat NCBP1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
NCBP1-3575R-B Recombinant Rat NCBP1 Protein Pre-coupled Magnetic Beads HEK293 Rat
Ncbp1-4304M Recombinant Mouse Ncbp1 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
NCBP1-5932M Recombinant Mouse NCBP1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
NCBP1-5932M-B Recombinant Mouse NCBP1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NCBP1 involved in several pathways and played different roles in them. We selected most pathways NCBP1 participated on our site, such as RNA transport,mRNA surveillance pathway,Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport EIF3G,NUPL1,EIF3HA,TGS1,WIBG,CYFIP1,FXR2,TACC3,RBM8A,EEF1A1L1
    Spliceosome SNW1,HNRNPUB,SRSF6A,DHX8,HSPA6,ISY1,SNRNP27,SFRS3B,BUD31,HNRNPA1A
    mRNA surveillance pathway MAGOHB,DDX39B,DAZAP1,NXT1,CPSF2,PABPC1L,PABPC1B,FIP1L1B,HBS1L,PPP2R1A

    Protein Function

    NCBP1 has several biochemical functions, for example, RNA binding,RNA cap binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NCBP1 itself. We selected most functions NCBP1 had, and list some proteins which have the same functions with NCBP1. You can find most of the proteins on our site.

    Function Related Protein
    RNA cap binding LARP1,EIF4A1,NCBP2,EIF4E2,SNUPN,EIF4G3,EIF4E
    protein binding BRD8,LRR1,TMPRSS4,SFRP4,TMEM182,EID1,PDXP,GAD1,ACSS1,BSG
    RNA binding ADARB2,POP4,HNRNPH1,PTBP1B,NHP2L1B,TRIM32,RPS3,RBM23,EIF2C3,SPI1
    poly(A) RNA binding EEF2,UTP15,SYNCRIP,POU5F1,EIF3L,RBM3,ZFP598,AHNAK,RRP9,NOP16

    Interacting Protein

    NCBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCBP1.

    NCBP2;RPS6;POLDIP3;PARN;EIF3B

    Resources

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