Recombinant Full Length Human MSX2 Protein, GST-tagged

• Cat.No.: MSX2-6477HF
• Product Overview: Human MSX2 full-length ORF ( AAH15509.1, 1 a.a. - 267 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 267 amino acids
• Description: This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
• Molecular Mass: 55 kDa
• AA Sequence: MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHTSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MSX2 msh homeobox 2 [ Homo sapiens ]
• Official Symbol: MSX2
• Synonyms: MSX2; msh homeobox 2; msh (Drosophila) homeo box homolog 2 , msh homeobox homolog 2 (Drosophila) , parietal foramina 1 , PFM1; homeobox protein MSX-2; craniosynostosis; type 2; CRS2; FPP; HOX8; MSH; PFM; msh homeo box 2; homeobox protein Hox-8; msh homeobox homolog 2; PFM1
• Gene ID: 4488
• mRNA Refseq: NM_002449
• Protein Refseq: NP_002440
• MIM: 123101
• UniProt ID: P35548