Recombinant Full Length Human LRRK1 Protein, GST-tagged

• Cat.No.: LRRK1-6078HF
• Product Overview: Human LRRK1 full-length ORF ( AAH68080.1, 1 a.a. - 261 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a multi-domain protein that is a leucine-rich repeat kinase and a GDP/GTP binding protein. The encoded protein is thought to play a role in the regulation of bone mass. Mice lacking a similar gene showed severe osteopetrosis, increased bone mineralization and decreased bone resorption. [provided by RefSeq, Jan 2017]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 55 kDa
• Protein length: 261 amino acids
• AA Sequence: MSQRPPSMYWCVGPEESAVCPERAMETLNGAGDTGGKPSTRGGDPAARSRRTEGIRAAYRRGDRGGARDLLEEACDQCASQLEKGQLLSIPAAYGDLEMVRYLLSKRLVELPTEPTDDNPAVVAAYFGHTAVVQELLESLPGPCSPQRLLNWMLALACQRGHLGVVKLLVLTHGADPESYAVRKNEFPVIVRLPLYAAIKSGNEDIAIFLLRHGAYFCSYILLDSPDPSKHLLRKYFIEASPLPSSYPGKTVSSHCLWSVF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LRRK1 leucine-rich repeat kinase 1 [ Homo sapiens ]
• Official Symbol: LRRK1
• Synonyms: LRRK1; leucine-rich repeat kinase 1; leucine-rich repeat serine/threonine-protein kinase 1; FLJ23119; KIAA1790; RIPK6; Roco1; FLJ27465
• Gene ID: 79705
• mRNA Refseq: NM_024652
• Protein Refseq: NP_078928
• MIM: 610986
• UniProt ID: Q38SD2