Recombinant Full Length Human Kcnj5 Protein, His tagged

• Cat.No.: KCNJ5-027HFL
• Product Overview: Recombinant Full Length Human Kcnj5 Protein with N-10×His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-419 aa
• Description: This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas.
• Tag: N-10×His
• Molecular Mass: 53.7 kDa
• AA Sequence: MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV
• Purity: > 90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade for twelve months from the date of receipt. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Lyophilized from 20 mM Tris-HCl, 0.15 M NaCl, 0.05% FOS12, 6% Trehalose, pH 8.0.
  The volume before lyophilization is 345 μL/vial.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20/-80 centigrade. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Gene Information

• Gene Name: KCNJ5 potassium inwardly rectifying channel subfamily J member 5 [ Homo sapiens (human) ]
• Official Symbol: KCNJ5
• Synonyms: KCNJ5; potassium inwardly rectifying channel subfamily J member 5; CIR; GIRK4; KATP1; LQT13; KIR3.4; G protein-activated inward rectifier potassium channel 4; IRK-4; cardiac ATP-sensitive potassium channel; heart KATP channel; inward rectifier K+ channel KIR3.4; potassium channel, inwardly rectifying subfamily J, member 5; potassium voltage-gated channel subfamily J member 5
• Gene ID: 3762
• mRNA Refseq: NM_000890
• Protein Refseq: NP_000881
• MIM: 600734
• UniProt ID: P48544