Recombinant Full Length Human IRAK1 Protein

• Cat.No.: IRAK1-257HF
• Product Overview: Recombinant full length Human IRAK with an N terminal proprietary tag; Predicted MWt 95.7 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 633 amino acids
• Description: This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: Liquid
• Molecular Mass: 95.700kDa inclusive of tags
• AA Sequence: MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPA DWCQFAALIVRDQTELRLCERSGQRTASVLWPWINRNARV ADLVHILTHLQLLRARDIITAWHPPAPLPSPGTTAPRPSS IPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHSGPELGL VPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPSPFCW PLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKR LKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQ NGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILL GTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFG LARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGR LAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLVYERLE KLQAVVAGVPGHLEAASCIPPSPQENSYVSSTGRAHSGAA PWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAAL RSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRP TAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDG ALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: IRAK1 interleukin-1 receptor-associated kinase 1 [ Homo sapiens ]
• Official Symbol: IRAK1
• Synonyms: IRAK1; interleukin-1 receptor-associated kinase 1; IRAK; pelle
• Gene ID: 3654
• mRNA Refseq: NM_001569
• Protein Refseq: NP_001560
• MIM: 300283
• UniProt ID: P51617