Recombinant Full Length Human HSD3B7 Protein, GST-tagged
Cat.No. : | HSD3B7-3884HF |
Product Overview : | Human HSD3B7 full-length ORF ( NP_079469.2, 1 a.a. - 369 a.a.) recombinant protein with GST-tag at N-terminal. |
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Species : | Human |
Source : | In Vitro Cell Free System |
Tag : | GST |
Protein Length : | 369 amino acids |
Description : | This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
Molecular Mass : | 67.4 kDa |
AA Sequence : | MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAARELEQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILWVQAATGSAQ |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name | HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [ Homo sapiens ] |
Official Symbol | HSD3B7 |
Synonyms | HSD3B7; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; 3 beta-hydroxysteroid dehydrogenase type 7; C(27) 3BETA HSD; SDR11E3; short chain dehydrogenase/reductase family 11E; member 3; 3-beta-HSD VII; C(27)-3BETA-HSD; c(27) 3-beta-HSD; 3 beta-hydroxysteroid dehydrogenase type VII; 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase; short chain dehydrogenase/reductase family 11E, member 3; CBAS1; PFIC4; |
Gene ID | 80270 |
mRNA Refseq | NM_025193 |
Protein Refseq | NP_079469 |
MIM | 607764 |
UniProt ID | Q9H2F3 |
◆ Recombinant Proteins | ||
RFL16774RF | Recombinant Full Length Rat 3 Beta-Hydroxysteroid Dehydrogenase Type 7(Hsd3B7) Protein, His-Tagged | +Inquiry |
HSD3B7-5081H | Recombinant Human HSD3B7 Protein, GST-tagged | +Inquiry |
RFL6198MF | Recombinant Full Length Mouse 3 Beta-Hydroxysteroid Dehydrogenase Type 7(Hsd3B7) Protein, His-Tagged | +Inquiry |
HSD3B7-3884HF | Recombinant Full Length Human HSD3B7 Protein, GST-tagged | +Inquiry |
HSD3B7-10193Z | Recombinant Zebrafish HSD3B7 | +Inquiry |
◆ Cell & Tissue Lysates | ||
HSD3B7-5368HCL | Recombinant Human HSD3B7 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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